Community General Hospital is located on Broad Road, near the intersection of West Seneca Turnpike (Route 173) on Onondaga Hill.

From Radisson and Clay: Travel south on Route 481 to Exit 1 (Brighton Avenue). Turn left on East Brighton Avenue at end of exit ramp. Take next right onto Route 173 (Seneca Turnpike). Continue across Salina Street and follow blue "H" signs to Community General Hospital. Travel time from Radisson, Route 481: approximately 30 minutes.

From North Syracuse: Travel south on Route 81 to Exit 17 (Brighton Avenue), to Salina Street. Left on Salina Street to Route 173 (Seneca Turnpike). Right onto Seneca Turnpike, then follow blue "H" signs to Community General Hospital. Travel time from Route 81 at Taft Road: approximately 15 minutes.

From the south: Travel north on Route 81. Take Exit 16 (Nedrow) to Salina Street. Travel north on Salina Street, then left to Route 173 (Seneca Turnpike). Follow blue "H" signs to Community General Hospital. Travel time from Nedrow exit: approximately 10 minutes.

From the east: Travel south on Route 481 to Exit 1 (Brighton Avenue). Turn left on East Brighton Avenue at end of exit ramp. Take next right onto Route 173 (Seneca Turnpike). Continue across Salina Street and follow blue "H" signs to Community General Hospital. Travel time from Lyndon Corners: approximately 15 minutes.

From the west: From Route 5 (Genesee Street), turn south onto Route 173 (Onondaga Road) at Fairmount Corners. Follow the blue "H" signs to Community General Hospital. Travel time from Fairmount Corners: approximately 10 minutes.